Table 1.

Association between PD-L1, IDO-1, B7-H4, TILs and clinico-pathological variables in cohort #1

Parameter	Stratification	PD-L1 low	PD-L1 high	P	IDO-1 low	IDO-1 high	P	B7-H4 low	B7-H4 high	P
Sex	Male	73	18	0.329	50	38	0.981	75	15	0.136
	Female	83	14		53	40		87	9
Age	<70y	106	22	0.891	76	57	0.168	115	13	0.116
	>70y	51	10		38	21		48	11
Stage	I-II	108	25	0.302	69	58	0.281	118	13	0.071
	III-IV	48	7		34	20		44	11
Histology	ADC	112	16	0.006	75	50	0.111	114	12	0.041
	SCC	26	7		17	14		24	9
	Other	12	9		7	13		19	2
CD3	Low	86	10	0.011	62	31	0.009	82	14	0.444
	High	72	22		43	47		82	10
CD8	Low	85	10	0.017	60	32	0.031	79	16	0.085
	High	73	22		45	46		85	8
CD20	Low	89	9	0.004	63	34	0.013	87	13	0.894
	High	72	23		45	50		85	12