Table 2.

Association between PD-L1, IDO-1, B7-H4, TILs and clinico-pathological variables in cohort #2

Parameter	Stratification	PD-L1 low	PD-L1 high	P	IDO-1 low	IDO-1 high	P	B7-H4 low	B7-H4 high	P
Sex	Male	168	57	0.005	146	139	0.289	190	59	0.261
	Female	31	2		16	22		32	6
Age	<70y	157	50	0.377	131	132	0.791	186	50	0.271
	>70y	40	9		30	28		35	14
Stage	I-II	112	42	0.031	92	100	0.293	135	37	0.527
	III-IV	85	16		69	59		82	27
Histology	ADC	83	19	0.068	62	64	0.323	102	12	<0.0001
	SCC	99	29		87	76		95	46
	Other	16	11		13	20		25	6
CD3	Low	115	18	0.0003	98	66	0.0004	109	39	0.125
	High	90	42		69	101		120	28
CD8	Low	121	16	<0.0001	102	63	<0.0001	108	39	0.111
	High	84	44		65	104		121	28
CD20	Low	114	23	0.012	109	62	<0.0001	115	37	0.6842
	High	91	37		61	111		118	34