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. 2019 Jan 10;2019:9141343. doi: 10.1155/2019/9141343

Table 2.

GSEA analysis on the biological processes regulated by the stress-induced premature senescence as compared to the untreated young control (p < 0.05).

GO accession Biological process NES p value
GO:0006576 Cellular biogenic amine metabolic process 1.33 2.63E − 02
GO:0044106 Cellular amine metabolic process 1.33 2.63E − 02
GO:0046885 Regulation of hormone biosynthetic process −1.40 3.17E − 02
GO:0051004 Regulation of lipoprotein lipase activity −1.32 3.28E − 02
GO:0070874 Negative regulation of glycogen metabolic process −1.44 3.39E − 02
GO:0032106 Positive regulation of response to extracellular stimulus −1.48 3.45E − 02
GO:0032109 Positive regulation of response to nutrient levels −1.48 3.45E − 02
GO:0031442 Positive regulation of mRNA 3′-end processing −1.24 3.57E − 02
GO:0043001 Golgi to plasma membrane protein transport −1.41 3.64E − 02
GO:2000973 Regulation of pro-B cell differentiation −1.69 3.77E − 02
GO:0032494 Response to peptidoglycan 1.40 3.85E − 02
GO:0006400 tRNA modification 1.50 3.92E − 02
GO:0045807 Positive regulation of endocytosis −1.34 4.11E − 02
GO:0006970 Response to osmotic stress −1.15 4.17E − 02
GO:0090199 Regulation of release of cytochrome c from mitochondria 1.29 4.35E − 02
GO:0042953 Lipoprotein transport −1.18 4.35E − 02
GO:0044872 Lipoprotein localization −1.18 4.35E − 02
GO:0061418 Regulation of transcription from RNA polymerase II promoter in response to hypoxia −1.52 4.35E − 02
GO:0048644 Muscle organ morphogenesis −1.70 4.35E − 02
GO:0022615 Protein to membrane docking −1.49 4.41E − 02
GO:0035563 Positive regulation of chromatin binding 1.55 4.44E − 02
GO:0048259 Regulation of receptor-mediated endocytosis −1.25 4.48E − 02
GO:0032922 Circadian regulation of gene expression −1.25 4.55E − 02
GO:0006694 Steroid biosynthetic process −1.37 4.55E − 02
GO:2001014 Regulation of skeletal muscle cell differentiation −1.57 4.55E − 02
GO:2000641 Regulation of early endosome to late endosome transport −1.31 4.62E − 02
GO:0043112 Receptor metabolic process −1.25 4.69E − 02
GO:0006891 Intra-Golgi vesicle-mediated transport −1.38 4.69E − 02
GO:0035330 Regulation of hippo signalling −1.44 4.69E − 02
GO:0035640 Exploration behavior −1.47 4.69E − 02
GO:0006270 DNA replication initiation 1.46 4.76E − 02
GO:0031536 Positive regulation of exit from mitosis 1.29 4.76E − 02
GO:0048020 CCR chemokine receptor binding −1.41 4.76E − 02
GO:0017144 Drug metabolic process −1.42 4.76E − 02
GO:2000095 Regulation of Wnt signalling pathway, planar cell polarity pathway −1.69 4.76E − 02
GO:0042347 Negative regulation of NF-kappaB import into nucleus −1.37 4.84E − 02
GO:0046854 Phosphatidylinositol phosphorylation −1.38 4.84E − 02
GO:0006901 Vesicle coating −1.42 4.84E − 02
GO:0051045 Negative regulation of membrane protein ectodomain proteolysis 1.62 4.88E − 02
GO:0006335 DNA replication-dependent nucleosome assembly 1.51 4.88E − 02
GO:0034723 DNA replication-dependent nucleosome organization 1.51 4.88E − 02
GO:2000649 Regulation of sodium ion transmembrane transporter activity −1.33 4.92E − 02
GO:0048260 Positive regulation of receptor-mediated endocytosis −1.35 4.92E − 02
GO:0002381 Immunoglobulin production involved in immunoglobulin-mediated immune response −1.36 4.92E − 02
GO:0018879 Biphenyl metabolic process −1.45 4.92E − 02