Table 2.
Allele and genotype frequencies of IRF7 SNPs in controls and AITD patients.
| SNP | Genotype/allele | Control (%) | AITD (%) | P | OR | 95% CI |
|---|---|---|---|---|---|---|
| rs1061501 | AA | 344 (44.7) | 423 (47.6) | |||
| AG | 357 (46.4) | 376 (42.3) | 0.237 | — | — | |
| GG | 69 (9.0) | 90 (10.1) | ||||
| A | 1045 (67.9) | 1222 (68.7) | 0.590 | 0.961 | 0.830-1.112 | |
| G | 495 (32.1) | 556 (31.3) | ||||
|
| ||||||
| rs1131665 | AA | 752 (97.7) | 849 (95.5) | |||
| AG | 18 (2.3) | 40 (4.5) | 0.017 | 1.968 | 1.119-3.463 | |
| GG | 0 (0) | 0 (0) | ||||
| A | 1522 (98.8) | 1738 (97.8) | 0.018 | 1.946 | 1.111-3.409 | |
| G | 18 (1.2) | 40 (2.2) | ||||
|
| ||||||
| rs1061502 | AA | 752 (97.7) | 851 (95.7) | |||
| AG | 18 (2.3) | 38 (4.3) | 0.029 | 1.866 | 1.056-3.296 | |
| GG | 0 (0) | 0 (0) | ||||
| A | 1522 (98.8) | 1740 (97.9) | 0.031 | 1.847 | 1.050-3.249 | |
| G | 18 (1.2) | 38 (2.1) | ||||
AITD, autoimmune thyroid disease; OR, odds ratio; 95% CI, 95% confidence intervals.