Table 4.
IRF7 genotype and allele distribution in ophthalmopathy or nonophthalmopathy GD patients.
| SNP | GD | P | OR (95% CI) | |
|---|---|---|---|---|
| Ophthalmopathy | Nonophthalmopathy | |||
| rs1061501 | — | — | — | — |
| AA | 41 (38.7%) | 240 (49.4%) | — | — |
| AG | 52 (49.1) | 206 (42.4%) | 0.102 | — |
| GG | 13 (12.3) | 40 (8.2%) | — | — |
| A | 134 (63.2%) | 686 (70.6%) | 0.035 | 1.396 (1.023-1.906) |
| G | 78 (32.8%) | 286 (29.4%) | — | — |
| rs1131665 | — | — | — | — |
| AA | 104 (99.1%) | 460 (97.3%) | — | — |
| AG | 2 (0.9%) | 26 (2.7%) | 0.128 | 2.939 (0.687-12.579) |
| GG | 0 (0%) | 0 (0%) | — | — |
| A | 210 (98.2%) | 946 (97.6%) | 0.133 | 2.886 (0.680-12.253) |
| G | 2 (1.8%) | 26 (2.4%) | — | — |
| rs1061502 | — | — | ||
| AA | 104 (99.1%) | 462 (95.1%) | — | — |
| AG | 2 (0.9%) | 24 (4.9%) | 0.259 | 2.701 (0.629-11.610) |
| GG | 0 (0%) | 0 (0%) | — | — |
| A | 210 (98.2%) | 948 (97.5%) | 0.265 | 2.658 (0.623-11.335) |
| G | 2 (1.8%) | 24 (2.5%) | — | — |
GD, Graves' disease; OR, odds ratio; 95% CI, 95% confidence intervals.