Table 6.
IRF7 genotype and allele distribution in clinical subphenotype of HT patients.
| SNP | HT | P | OR (95% CI) | |
|---|---|---|---|---|
| Hypothyroidism | Nonhypothyroidism | |||
| rs1061501 | — | — | — | — |
| AA | 94 (48.5%) | 48 (46.6%) | — | — |
| AG | 73 (37.6) | 45 (43.7%) | 0.443 | — |
| GG | 27 (13.9) | 10 (9.7%) | — | — |
| A | 261 (67.3%) | 141 (68.4%) | 0.770 | 0.947 (0.659-1.361) |
| G | 127 (32.7%) | 65 (31.6%) | — | — |
| rs1131665 | — | — | — | — |
| AA | 187 (96.4%) | 98 (95.1%) | — | — |
| AG | 7 (3.6%) | 5 (4.9%) | 0.834 | 1.363 (0.422-4.406) |
| GG | 0 (0%) | 0 (0%) | — | — |
| A | 381 (98.2%) | 201 (97.6%) | 0.836 | 1.354 (0.424-4.320) |
| G | 7 (1.8%) | 5 (2.4%) | — | — |
| rs1061502 | — | — | ||
| AA | 187 (96.4%) | 98 (95.1%) | — | — |
| AG | 7 (3.6%) | 5 (4.9%) | 0.834 | 1.363 (0.422-4.406) |
| GG | 0 (0%) | 0 (0%) | — | — |
| A | 381 (98.2%) | 201 (97.6%) | 0.836 | 1.354 (0.424-4.320) |
| G | 7 (1.8%) | 5 (2.4%) | — | — |
HT, Hashimoto's thyroiditis; OR, odds ratio; 95% CI, 95% confidence intervals.