. 2018 Nov 16;11(1):183–200. doi: 10.1039/c8mt00239h

Table 4. All proteins whose abundances were significantly changed after growth for 6 h in TM medium in the presence of 1.5 mM CuSO₄, relative to control cells in TM alone, as determined by LC-MS/MS. Column ‘P’ shows statistical significance using the Fisher's exact test.

Protein	Gene	ORF	GI	Fold	P
Proteins with increased abundance in cells cultured in 1.5 mM Cu in TM medium
Copper chaperone CopZ	copZ	SAOUHSC_02874	gi\|122538627	5.3	<0.00010
d-Alanine-poly(phosphoribitol) ligase subunit 1	dltA	SAOUHSC_00869	gi\|122539917	1.4	<0.00010
50S ribosomal protein L29	rpmC	SAOUHSC_02504	gi\|122538860	1.4	0.00017
2,3-Bisphosphoglycerate-dependent phosphoglycerate mutase	gpmA	SAUOHSC_02703	gi\|122538743	1.1	<0.00010
Alkyl hydroperoxide reductase subunit C	ahpC	SAOUHSC_00365	gi\|60391219	1.1	<0.00010
Catalase	katA	SAOUHSC_01327	gi\|126215678	<1.1	<0.00010

Proteins with decreased abundance in cells cultured in 1.5 mM Cu in TM medium
Fructose-bisphosphate aldolase	fda	SAOUHSC_02926	gi\|446954157	0.9	<0.00010
Glutamine synthetase	glnA	SAOUHSC_01287	gi\|447049347	0.9	<0.00010
Transketolase	tkt	SAOUHSC_01337	gi\|446403588	0.8	<0.00010
Histone-like DNA-binding protein HU	hup	SAOUHSC_01490	gi\|446966607	0.8	<0.00010
30S ribosomal protein S1	rpsA	SAOUHSC_01493	gi\|88195210	0.8	<0.00010
Hypothetical protein, family UPF0342	—	SAOUHSC_01977	gi\|122539212	0.8	<0.00010
30S ribosomal protein S7	rpsG	SAOUHSC_00528	gi\|110282992	0.7	0.00015
Branched-chain alpha-keto acid dehydrogenase subunit E2	pdhC	SAOUHSC_01042	gi\|88194794	0.6	<0.00010
Bifunctional autolysin	atl	SAOUHSC_00994	gi\|110832765	0.6	0.00038
Pyruvate carboxylase	pycA	SAOUHSC_01064	gi\|88194813	0.6	<0.00010
Phosphoribosylamine-glycine ligase	purD	SAOUHSC_01018	gi\|88194772	0.6	0.00074
DNA-directed RNA polymerase subunit beta′	rpoC	SAOUHSC_00525	gi\|114152142	0.5	0.00013
Elongation factor Tu	tuf	SAOUHSC_00530	gi\|123098060	0.2	<0.00010
Alkaline shock protein 23	asp23	SAOUHSC_02441	gi\|446137381	0.1	<0.00010
Cell division protein FtsZ	ftsZ	SAOUHSC_01150	gi\|122539740	0.08	0.00052
l-Lactate dehydrogenase 1	ldh	SAOUHSC_00206	gi\|205438378	OFF	<0.00010
50S ribosomal protein L23	rplW	SAOUHSC_02510	gi\|123003430	OFF	<0.00010
Cold-shock protein	cspC	SAOUHSC_00819	gi\|446981826	OFF	<0.00010
50S ribosomal protein L13	rplM	SAOUHSC_02478	gi\|122538869	OFF	<0.00010
50S ribosomal protein L18	rplR	SAOUHSC_02495	gi\|115504959	OFF	0.00012

Table 4. All proteins whose abundances were significantly changed after growth for 6 h in TM medium in the presence of 1.5 mM CuSO4, relative to control cells in TM alone, as determined by LC-MS/MS. Column ‘P’ shows statistical significance using the Fisher's exact test.

Table 4. All proteins whose abundances were significantly changed after growth for 6 h in TM medium in the presence of 1.5 mM CuSO₄, relative to control cells in TM alone, as determined by LC-MS/MS. Column ‘P’ shows statistical significance using the Fisher's exact test.