Table 2.

Serum creatinine levels preoperatively, 6, 24 and 48 hours postoperatively; plasma NGAL levels preoperatively and at arrival in ICU, plasma HO-1 levels preoperatively, at arrival in ICU and 24 hours postoperatively according to AKI 24 hours postoperatively

	All patients	No AKI	AKI	P-value
Creatinine preoperative (mg/dL)	0.92 (0.76–1.04)	0.90 (0.75–1.02)	1.00 (0.78–1.23)	0.535
Creatinine 6 h (mg/dL)	1.01 (0.83–1.04)	0.95 (0.78–1.11)	1.21 (1.09–1.50)	0.001
Creatinine 24 h (mg/dL)	0.99 (0.81–1.23)	0.90 (0.75–1.04)	1.37 (1.20–1.78)	<0.001
Creatinine 48 h (mg/dL)	0.97 (0.83–1.27)	0.89 (0.77–1.07)	1.68 (1.32–2.06)	<0.001
NGAL preoperative (pg/mL)	352 (278–466)	336 (271–468)	360 (304–616)	0.80
NGAL ICU (pg/mL)	628 (490–828)	600 (461–783)	960 (614–1262)	<0.001
HO-1 preoperative (ng/mL)	7.34 (4.63–9.66)	6.98 (4.44–9.01)	6.29 (4.48–10.88)	0.83
HO-1 ICU (ng/mL)	12.81 (8.81–19.59)	12.91 (8.73–19.54)	11.65 (9.95–21.49)	0.88
HO-1 24 h (ng/mL)	9.71 (4.49–16.75)	8.30 (4.13–15.60)	12.75 (8.69–34.35)	0.031

Notes: Data is presented as median (IQR25, IQR75). The bold values are statistically significant.

Abbreviations: AKI, acute kidney injury; HO-1, heme oxygenase 1; ICU, intensive care unit; NGAL, neutrophil gelatinase-associated lipocalin.