Table 3.
Characteristics | Our study (FUSCC China) | Lee et al,9 Korea | χ2 | P-value | Kim et al,11 Korea | χ2 | P-value |
---|---|---|---|---|---|---|---|
| |||||||
N=28 | N=262 | N=208 | |||||
| |||||||
Gender | |||||||
Male | 18 | 170 | 0.004 | 0.950 | 131 | 0.018 | 0.893 |
Female | 10 | 92 | 77 | ||||
Age at diagnosis (years) | |||||||
>60 | 3 | 55 | 1.670 | 0.196 | 141 | 33.796 | <0.001 |
≤60 | 25 | 207 | 67 | ||||
ECOG | |||||||
0–1 | 13 | 228 | 29.688 | <0.001 | 187 | 36.082 | <0.001 |
2–3 | 15 | 34 | 21 | ||||
Ann Arbor stage | |||||||
I + II | 19 | 200 | 0.984 | 0.321 | 145 | 0.040 | 0.841 |
III + IV | 9 | 62 | 63 | ||||
LDH before HLH | |||||||
Normal | 13 | 166 | 0.159 | 0.69 | 125 | 0.008 | 0.927 |
Elevated | 9 | 96 | 83 | ||||
Subtypes | |||||||
UNKTL | 16 | 222 | 13.085 | <0.001 | 167 | 7.592 | 0.006 |
EUNKTL | 12 | 40 | 41 | ||||
NKPI | |||||||
0–1 | 18 | 128 | 0.35 | 0.554 | 110 | 1.292 | 0.25 |
≥2 | 10 | 91 | 98 | ||||
Cutaneous involvement | |||||||
Yes | 10 | 7 | 50.049 | <0.001 | NA | ||
No | 18 | 255 | NA |
Abbreviations: ECOG, Eastern Cooperative Oncology Group; EUNKTL, extra-upper aerodigestive tract NK/T-cell lymphoma; FUSCC, Fudan University Shanghai Cancer Center; HLH, hemophagocytic lymphohistiocytosis; LDH, lactic dehydrogenase; NKPI, NK/T-cell lymphoma prognostic index; UNKTL, upper aerodigestive tract NK/Tcell lymphoma.