Table 4.
The physiochemical properties, antimicrobial activity and hemolytic activity of published naturally occurring phylloseptins
| Peptide | MIC (µM) | Hydrophobicity <H> | Hydrophobic moment <µH> | Net charges (pH 7.4) | HC50 | ||
|---|---|---|---|---|---|---|---|
| Staphylococcus aureus | Escherichia coli | Candida albicans | |||||
| PSN-PC20 | 2 | 8 | 2 | 0.754 | 0.563 | +2 | 23 |
| PS-PTa5 | 4.1 | 16.6 | 2.1 | 0.740 | 0.577 | +2 | 22.8 |
| PS-Du23 | 3.90 | 62.5 | 7.8 | 0.725 | 0.624 | +2 | 95 |
| PS-PBa22 | 4.2 | 67.6 | 4.2 | 0.711 | 0.637 | +2 | 90 |
| PS-Co23 | 4.1 | 64.9 | 8.1 | 0.706 | 0.636 | +2 | 115 |
| PS-PT3 | 264 | >264 | 264 | 0.707 | 0.418 | +2 | >264 |
Abbreviations: HC50, half maximal hemolysis concentration; MIC, minimum inhibitory concentration.