Table 1.
Summary of the baseline characteristics of patients in the GEO-, TCGA- and Cirenajwis-dataset.
Patient & tumour characteristics | GEO-dataset n (%) | TCGA-dataset n (%) | Cirenajwis-dataset n (%) | |||
---|---|---|---|---|---|---|
Total number of patients | 405 | 469 | 214 | |||
Sex | ||||||
Male | 129 (31.9) | 289 (61.6) | 124 (57.9) | |||
Female | 101 (24.9) | 180 (38.4) | 89 (41.6) | |||
NA | 175 (43.2) | 0 (0) | 1 (0.5) | |||
Age (yrs) | ||||||
Median (IQR) | 66 (51–78) | 58 (48–71) | 64 (54–74) | |||
Tumour stage (AJCC 7th ed.) | ||||||
Tumour in situ (stage 0) | 0 (0) | 7 (1.5) | 0 (0) | |||
Low stage (stage I or II) | 22 (5.4) | 235 (50.1) | 0 (0) | |||
High stage (stage III or IV) | 363 (89.6) | 191 (40.7) | 214 (100) | |||
NA | 20 (4.9) | 36 (7.7) | 0 (0) | |||
Sample obtained from | ||||||
Primary tumour | 56 (13.8) | 102 (21.7) | 16 (7.5) | |||
Lymph node metastasis | 15 (3.7) | 229 (48.9) | 128 (59.8) | |||
Regional | Unknown | 222 (47.3) | 127 (59.3) | |||
Distant | Unknown | 7 (1.5) | 1 (0.5) | |||
(Sub)cutaneous or in transit metastasis | 108 (26.7) | 99 (21.1) | 41 (19.2) | |||
Visceral metastasis | 20 (2.5) | 26 (5.5) | 10 (4,7) | |||
Bone metastasis | 0 (0) | 6 (1.3) | 0 (0) | |||
CNS metastasis | 0 (0) | 2 (0.4) | 0 (0) | |||
Unknown location of distant metastasis | 155 (38.3) | 2 (0.4) | 19 (8.9) | |||
Unknown primary or metastatic lesion | 51 (12.6) | 3 (0.6) | 0 (0) |
Abbreviations: CNS: Central nervous system, ed.: edition, NA: Not Available, IQR: Interquartile range, yrs: years.