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In vitro release of ranibizumab from degradable microsphere-hydrogel DDS with varying PEG-PLLA-DA concentrations and 10 mg/mL microsphere load amount. “1 mM,” “2 mM,” and “3 mM” in the legend represent PEG-PLLA-DA concentrations for hydrogels; “DDS-10” stands for 10 mg/mL microsphere load amount. (a) Percent cumulative release of ranibizumab from investigated DDS. (b) Cumulative release of ranibizumab in weight (μg). Error bars represent standard error (n = 3).
