Table 2.
Characteristics of Ranibizumab Release
| DDS Formulation |
Drug Total Load Amount (μg) |
IB Release (%) |
Release Rate After 7 Days (μg/Day) |
Release Time (Days) |
Final Percent Release (%) |
| 1 mM DDS-10 | 11.99 ± 2.92 | 19.03 ± 1.38 | 0.02 (r2 = 0.99) | 176 | 56.89 ± 2.01 |
| 2 mM DDS-10 | 14.30 ± 5.20 | 18.84 ± 4.09 | 0.03 (r2 = 0.99) | 176 | 61.90 ± 4.81 |
| 3 mM DDS-10 | 15.78 ± 5.68 | 21.13 ± 1.64 | 0.04 (r2 = 0.99) | 176 | 78.52 ± 3.84 |
Daily release rates after 7 days were estimated using linear regression. Data presented as mean ± SEM (n = 3).