Fig 4. Cytotoxic effects of vorinostat and cisplatin in PANC-1 cells, alone and in combination at concentrations: 1 (7.5 and 10 μM), 2 (15 and 20 μM) and 3 (30 and 40 μM) after 72 h of exposure.

Data is presented as means ± SDs from 4 replicates (vorinostat and combination) or 8 replicates (cisplatin) per concentration. Dose-reduction index (DRI) plot is shown on the right.