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. 2018 Nov 26;10(11):e3635. doi: 10.7759/cureus.3635

Table 1. Type 1 and Type 2 Renal Tubular Acidosis (RTA).

    Distal (Type 1) RTA   Proximal (Type 2) RTA   Study Ref.
  Pathophysiology   Failure to secrete H+ and reabsorb K+ Ions     Failure to reabsorb HCO3    
  Location   Collecting & distal tubules     Proximal Tubules    
  Urine pH     > 6.0     <5.5     13
  Urine HCO3-       Normal     Increased     13
  Fractional Excretion of HCO3-   <5%    >15%   13
  Serum Potassium     Hypokalemia     Hypokalemia