Figure 16. Dexrazoxane prevents AIF release from isolated mitochondria. Track 1 = Control; track 2 = 100 nM PAR and 100 nM dexrazoxane; track 3 = 100 nM PAR and 50 nM dexrazoxane; track 4 = 100 nM PAR and 10 nM dexrazoxane. PAR and dexrazoxane were incubated together for 10 minutes before adding to the mitochondrial suspension (western blots reproduced from the study final report).
