Table 2.
Variable | Location of PE | Total (n = 271) | Central versus peripheral PE, p value | ||
---|---|---|---|---|---|
Central (n = 33) | Segmental (n = 164) | Subsegmental (n = 74) | |||
Clinical and pathologic characteristics | |||||
Age at PE (y) | 65.1 ± 12.2 | 63.4 ± 12.8 | 62.1 ± 13.4 | 63.2 ± 12.9 | NS* |
Male | 46.7% | 36.2% | 35.5% | 37.2% | NS |
BMI | 28.1 ± 5.2 | 27.1 ± 5.7 | 28.9 ± 8.9 | 27.7 ± 6.8 | |
Type of surgery, % | |||||
Thoracotomy | 15.2 | 12.8 | 13.5 | 13.3 | |
Laparotomy-abdominal | 57.6 | 26.8 | 31.1 | 31.7 | |
Laparotomy-pelvic | 21.2 | 54.3 | 44.6 | 47.6 | |
Laparoscopy/thoracoscopy | 0 | 4.3 | 10.8 | 5.5 | |
Soft tissue resection | 6.1 | 1.8 | 0 | 1.8 | |
Cancer site, % | |||||
Thoracic | 12.1 | 9.1 | 14.9 | 11.1 | |
Colorectal | 12.1 | 13.4 | 8.1 | 11.8 | |
GI (other) | 9.1 | 6.7 | 8.1 | 7.4 | |
Hepatobiliary/pancreatic | 0.0 | 0.6 | 0.0 | 0.4 | |
Genitourinary | 24.2 | 21.3 | 23.0 | 22.1 | |
Gynecologic | 21.2 | 36.0 | 39.2 | 35.1 | |
Soft tissue tumor | 6.1 | 3.7 | 1.4 | 3.3 | |
Other | 0.0 | 3.7 | 0.0 | 2.2 | |
Pathologic stage, % | NS* | ||||
0 | 5.3 | 0.0 | 2.4 | 1.1 | |
I | 21.1 | 26.2 | 20.4 | 24.0 | |
II | 21.1 | 19.6 | 18.4 | 19.4 | |
III | 42.1 | 27.1 | 34.7 | 30.9 | |
IV | 10.5 | 27.1 | 24.5 | 24.6 | |
PE symptoms and severity | |||||
Complication grade, % | < .001 | ||||
1 | 0.0 | 0.6 | 6.6 | 2.2 | |
2 | 53.3 | 84.1 | 85.5 | 81.0 | |
3 | 13.3 | 12.9 | 6.6 | 11.2 | |
4 | 0.0 | 1.2 | 0.0 | 0.7 | |
5 | 33.3 | 1.2 | 1.3 | 4.8 | |
Clinical symptoms, % | |||||
Shortness of breath | 67.9 | 48.5 | 58.7 | 53.4 | .041 |
SaO2 < 92% | 74.1 | 36.7 | 40.5 | 41.6 | < .001 |
Heart rate > 100 bpm | 85.2 | 61.7 | 61.3 | 64.0 | .007 |
Chest pain | 14.3 | 8.7 | 10.8 | 9.9 | NS |
Hemoptysis | 0.0 | 0.0 | 1.3 | 0.4 | NS |
Clinical DVT | 17.9 | 10.5 | 6.8 | 10.2 | NS |
ICU admission | 39.3 | 19.3 | 20.0 | 21.6 | .018 |
Cardiopulmonary arrest | 27.6 | 5.6 | 8.0 | 8.7 | .013 |
Concurrent DVT** | 56.3 | 37.5 | 22.2 | 34.8 | NS |
Anticoagulation. % | |||||
Pharmacologic prophylaxis | 60.7 | 56.6 | 55.3 | 56.7 | NS |
Bleeding complications | 13.8 | 14.5 | 14.5 | 14.4 | NS |
Followup. % | |||||
Second VTE event | 6.9 | 11.0 | 9.2 | 10.1 | NS |
30-d PE mortality | 33.3 | 4.9 | 5.4 | 8.5 | < .001 |
Continuous variables compared with t-test for independent samples.
BMI, body mass index; DVT, deep vein thrombosis; GI, gastrointestinal; ICU, intensive care unit; VTE, venous thromboembolic event.