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. 2018 Dec 10;8(2):e1544442. doi: 10.1080/2162402X.2018.1544442

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© 2018 The Author(s). Published with license by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 2. — Tumour PD-L1, CD3 and CD8 marker expression are prognostic for improved survival.

Kaplan-Meier estimates of overall survival (OS) and disease-free survival (DFS) according to (a) PD-L1 tumour cell (TC) positivity, (b) PD-L1 immune cell (IC) positivity, (c) CD3 + T cell densities, and (d) CD8+ cytotoxic T cell densities. The cut-offs used were PD-L1 TC and IC (≥ 1%), CD3 (500 cells/mm2) and CD8 (600 cells/mm2). Data were statistically analysed by Cox Proportional Hazards (*P < 0.05, **P < 0.01, ***P < 0.001).