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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Hepatology. 2018 Dec 31;69(2):860–875. doi: 10.1002/hep.30229

Figure 5. Activation of mTOR signaling in X/A-like cells increases brown phenotype of BAT and WAT depots.

Figure 5.

Histology of BAT (a), sWAT (c) and eWAT (e) shown by HE staining. mRNA levels of brown- and white- adipocyte marker genes were detected by RT-qPCR in BAT (b), sWAT (d) and eWAT (f), and normalized to β-actin. Fold changes were expressed as mean±SEM. n=20 for each group. *P<0.05 vs. wild-type mice fed NCD; # P<0.05 vs. wild-type littermates fed HFD (Student’s t test). Mice were placed in cold room (4°C) for 6 hours and rectal temperature was measured every hour (g). n=6 per group. *P<0.05 indicates TG vs. wild-type mice fed HFD.