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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Stress. 2018 Jun 22;22(1):36–43. doi: 10.1080/10253890.2018.1484445

Table 2:

Associations between thymic indices and 6 wk vaccination-induced cortisol responsiveness (∆Cortisol) in infants determined by multivariate regression modelling

Male
Female
Regression model
∆Cortisol (µg/dL)
Regression model
∆Cortisol (µg/dL)
R2 p β (SE) p R2 P β (SE) p
Thymic index
   1 w 0.243 0.016 −5.50 (1.81) 0.0032 0.346 <0.001 1.60 (1.46) 0.28
   6 w 0.315 <0.001 −10.4 (2.95) <0.001 0.216 0.0085 −1.278 (2.97) 0.67
   10 w 0.286 0.0028 −11.6 (3.21) <0.001 0.172 0.021 −2.309 (2.92) 0.43
   15 w 0.222 0.034 −12.5 (3.27) <0.001 0.204 0.014 −1.99 (3.04) 0.51

Regression models determined association between thymic index and cortisol response (∆Cortisol) controlling the factors: infant’s behaviour during saliva collection, saliva collection time, pre-vaccine cortisol, mode of delivery, birthweight, length for age Z-score, weight for length Z-score, and breastfeeding status. 1 w regression model was determined by using birthweight and birth length instead of weight for length and length for age Z-scores, respectively.