Table 4:
Associations between vaccine responses and 6-week vaccination induced cortisol responsiveness in infants
Regression model |
∆Cortisol (µg/dL) |
|||
---|---|---|---|---|
R2 | p | β (SE) | p | |
CD4+ T-cell SI at 6 w | ||||
PPD | 0.119 | 0.23 | −0.286 (0.958) | 0.77 |
SEB | 0.0947 | 0.46 | −1.22 (1.18) | 0.30 |
CD4+ T-cell SI at 15 w | ||||
PPD | 0.0718 | 0.48 | 0.428 (1.08) | 0.69 |
SEB | 0.0676 | 0.68 | −0.517 (1.01) | 0.61 |
TT | 0.0786 | 0.36 | 40.5 (58.2) | 0.49 |
HBV | 0.141 | 0.024 | 34.1(55.7) | 0.54 |
ALS antibody at 15 w | ||||
TT IgG, mIU/mL | 0.0592 | 0.564 | −1.26 (1.33) | 0.35 |
Polio IgG, mIU/mL | 0.0933 | 0.14 | 1.26e-06 (6.75e-07) | 0.065 |
HBV IgG, mIU/mL | 0.157 | 0.13 | −0.0197 (0.0245) | 0.43 |
PPD skin test at 15 w | ||||
Area (cm2) | 0.0659 | 0.37 | −110.4 (55.8) | 0.049 |
Positive (n=187), Negative = 0 (n=37) |
-- | −5.31 (2.51) | 0.034 |
Regression models determined association between vaccine response and cortisol response (∆Cortisol) controlling the factors: infant’s behaviour during saliva collection, pre-vaccine cortisol, saliva collection time, sex, mode of delivery, birthweight, length for age Z-score, weight for length Z-score, and breastfeeding status.