Table 6. Summary of recommended adjuvant therapy.

CD117/C-Kit mutation	Imatinib	Sunitinib	Ponatinib
Exon 9	–	Standard dosing‡	–
Exon 11	Early: low dose†; late: high dose†	–	–
Exon 13	–	Standard dosing‡	–
Exon 14	–	Standard dosing‡	–
Exon 17	–	–	Standard dosing‡
No exon mutation	–	Standard dose‡	–

^†, denotes high dose: (800 mg/day); low dose: (400 mg/day); ^‡, standard dosing according to established protocol (28,30).