TABLE 1.

Summary of measures of health-related quality of life used in pulmonary arterial hypertension (PAH)

Measure [ref.]	Domains	Items n	Recall period
Generic
SF-36 [9]	Physical functioning, role limitations physical, bodily pain, general health, vitality, social functioning, role limitations emotional, mental health	36	Now to past 4 weeks
EQ-5D [10]	Health state description: mobility, self-care, usual activities, pain/discomfort, anxiety/depression; overall health status (visual analogue scale)	51	Today
NHP [11]	Mobility, pain, social isolation emotional reactions, energy level, sleep	38	At the moment
HADS [12]	Anxiety, depression	14	At the moment
PAH specific
CAMPHOR [13]	Overall symptoms (energy, breathlessness, mood), functioning, quality of life	65	Today
MLHFQ [14]	Physical, emotional	21	4 weeks
LPH [15]	Physical, emotional	21	1 week
CHFQ [16]	Dyspnoea, fatigue, emotional function, mastery	20	2 weeks
emPHasis-10 [17]	Unidimensional	10	At the moment
PAH-SYMPACT [18]	Respiratory symptoms, tiredness, cardiovascular symptoms, other symptoms, physical activities, daily activities, social impact, cognition, emotional impact	41	24 h for symptoms; 7 days for imacts

SF-36: Medical Outcomes Study 36-item short form; EQ-5D: EuroQol Group 5-Dimension Self-Report Questionnaire; NHP: Nottingham Health Profile; HADS: Hospital Anxiety and Depression Scale; CAMPHOR: Cambridge Pulmonary Hypertension Outcome Review; MLHFQ: Minnesota Living with Heart Failure Questionnaire; LPH: Living with Pulmonary Hypertension questionnaire; CHFQ: Chronic Heart Failure Questionnaire; emPHasis-10: 10-question survey proposed by the Pulmonary Hypertension Association UK. Information based on and expanded from [6].