Figure 1.
Experimental groups. Overview of experimental procedures. Grip strength was measured daily and started at the time of inoculation in experiment 1 and five days before inoculation in experiment 2. Mice of the Blank group did not receive any inoculation nor any intraperitoneal injections with ceftriaxone (antibiotics). Mice of the control groups were inoculated with saline and the other experimental groups with ~2×105 colony forming units of S. pneumoniae. Mice of the Control1 and AB24 group received their first ceftriaxone administration at 24 hours after inoculation, mice of the Control2 and AB48 group at 48 hours after inoculation and mice of the ABWL group as soon as they lost 10% of their body weight. Mice in experiment 1 received a total of three injections with ceftriaxone and mice in experiment 2 received two injections.