Table 2. Electrophysiological measurements of the sciatic and caudal nerve.
| Nerve | Measurement | Experiment 1 | Experiment 2 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Blank, N=4 | Control1, N=4 | AB24, N=8 | P | Control2, N=4 | AB48, N=6 | ABWL, N=6 | P | |||
| Sciatic nerve | CMAP (mV) | 7.9 (5.1–11.4) | 8.7 (6.7–10.0) | 11.7 (9.2–13.9) | 0.43 | 5.3 (3.1–7.8) | 8.9 (7.7–11.0) | 11.8 (9.2–15.2)* | 0.08 | |
| NCV (m/s) | 43.0 (41.8–47.5) | 42.5 (41.8–43.5) | 42.5 (42.0–45.0) | 0.91 | 37 (34.5–41.0) | 36 (31.5–39.8) | 31 (30.0–33.0) | 0.21 | ||
| Caudal nerve | CNAP (µV) | 114.8 (101.7–140.9) | 110.3 (93.9–128.3) | 131.1 (118.2–146.0) | 0.50 | 106.4 (100.0–122.5) | 111.8 (95.3–124.4) | 129.3 (98.1–145.7) | 0.94 | |
| NCV (m/s) | 41.0 (38.8–43.3) | 40.0 (38.8–41.3) | 41.0 (38.5–42.5) | 0.85 | 33.5 (29.8–37.3) | 44.5 (41.0–47.3)* | 41.0 (38.8–42.5) | 0.05 | ||
*, P<0.05 compared to Control2 group. Nerve conduction measurements presented as median with interquartile range. CMAP, compound muscle action potential; CNAP, compound nerve action potential; NCV, nerve conduction velocity.