Table 3.
RTOG late-term GI/GU toxicities (n = 26)
| Grade | All patients (n = 26) |
S-IL-2 (n = 13) |
M-IL-2 (n = 13) |
P-value | |||
|---|---|---|---|---|---|---|---|
| GU (%) | GI (%) | GU (%) | GI (%) | GU (%) | GI (%) | ||
| 0 | 19 (73) | 17 (65) | 10 (77) | 9 (69) | 9 (69) | 8 (62) | |
| 1 | 2 (8) | 7 (27) | 0 (0) | 2 (15) | 2 (15) | 5 (38) | |
| 2 | 4 (15) | 2 (8) | 2 (15) | 2 (15) | 2 (15) | 0 (0) | |
| 3 | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | |
| 4 | 1 (4) | 0 (0) | 1 (8) | 0 (0) | 0 (0) | 0 (0) | |
| ≥2 | 5 (19) | 2 (8) | 3 (23) | 2 (15) | 2 (15) | 0 (0) | GU: 1.00 GI: 0.48 |
Abbreviations: GI, gastrointestinal; GU, genitourinary; IL, interleukin; M-IL-2, metronomic dose IL-2; RTOG, Radiation Therapy Oncology Group; S-IL-2, standard dose IL-2.