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. 2019 Jan 23;10:15. doi: 10.3389/fphar.2019.00015

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Copyright © 2019 Li, Zhao, Yang, Zhang, Kang, Deng, Xu, Ding and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The immunofluorescence intensities analysis of Smad3 expression in MCCs. MCCs were transfected with or without miR-140-5p mimic for 48 h, then stimulated with or without IL-1β for 24 h, respectively. Scale bar = 10 μm (magnification, ×200). Typical confocal micrographs of Smad3 showed in green, and DAPI in blue. Data are represented as means ± standard deviation (n = 3). ^∗P < 0.05 when compared with the negative control group (NC). ^###P < 0.001 when compared with NC induced by IL-1β.