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. 2019 Jan 23;9:3325. doi: 10.3389/fmicb.2018.03325

FIGURE 2.

FIGURE 2

Sketch of different medication modes. Prophylactic administration: drugs added to the cell culture before the infectious virus was added to A549 cells. Premixed administration: drugs and virus were mixed, incubated at 4°C for 1 h, and then added to the cell culture mixture. Simultaneous administration: Drugs and virus were mixed and immediately added to the cell culture. Therapeutic administration: drugs were added after infection by the virus to A549 cells. Green: the period of cell culture; Yellow: in this time, the drug was in the medium; Red: the time of the virus infection; Magenta: drugs and the virus in the medium at the same time; Blue: there was cell culture without drugs and virus; Black: this was the period of detection.