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. 2019 Jan 23;13:16. doi: 10.3389/fnins.2019.00016

FIGURE 6.

FIGURE 6

Target Gene Prediction of miRNA-7a-2-3p. (A) The intersections of the predicted target genes results of miR-7a-2-3p in TargetScan, miRDB, miRwalk and miRNA sequencing are presented. The different colors represent distinctive methods of prediction. There were five target genes of miR-7a-2-3p, including VIM, PLAG1, DUSP10, NQO1, and TNFRSF1B. (B) The qRT-PCR analysis showed that VIM, PLAG1, DUSP10, NQO1, and TNFRSF1B. VIM, PLAG1, DUSP10, NQO1, and TNFRSF1B were significantly increased in the HI group compared with the sham group (∗∗P < 0.01). (C) Alignment of the seed regions of miR-7a-2-3p with 3’-UTR of VIM, PLAG1, DUSP10, NQO1, and TNFRSF1B is shown. The red color indicated the pairing bases.