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. 2019 Jan 23;9:720. doi: 10.3389/fgene.2018.00720

Table 1.

Summary of RNAi and CRISPR-Cas9 genome-wide knockout experiment characteristics for the study of HIV disease.

Study (Year) Type of screen Cell types1 HIV-1 strains2 Reference
Brass et al., 2008 RNAi HeLa-derived TZM-bl cells HIV-1 IIIB Brass et al., 2008
König et al., 2008 RNAi HEK-293 T cells HIV-1 VSV-G König et al., 2008
Zhou et al., 2008 RNAi HeLa P4-R5 HIV-1 HXB2 Zhou et al., 2008
Zhu et al., 2014 RNAi HeLa MAGI HIV-1 IIIB Zhu et al., 2014
Park et al., 2017 CRISPR GXRCas9 HIV-1 JR-CSF Park et al., 2017

1Cell types used for RNAi or CRISPR screening. 2HIV-1 strains used for RNAi screens.