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Patient 2. a T2-weighted FLAIR MRI shows a hyperintense tumor with small cystic regions in the left frontal lobe. b MET PET shows the hotspot region of the tumor. c DSC perfusion MRI with rCBV greyscale map shows higher perfusion in the region corresponding to the PET hotspot. d Co-registration of MRI, PET, and corresponding histological images with defined ROIs (ROI1, red and orange; ROI2 yellow, ROI3 green)
