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Patient 3. a T2-weighted FLAIR MRI shows a hyperintense tumor in the left frontal lobe. b MET PET shows the hotspot regions of the tumor. c DSC perfusion MRI with rCBV greyscale map shows low or normal perfusion in the region corresponding to the PET hotspot. d Co-registration of MRI, PET, and corresponding histological images with defined ROIs (ROI1, red and orange; ROI2 yellow). There was no identifiable ROI3 in this sequence
