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. 2019 Jan 29;9:867. doi: 10.1038/s41598-018-37242-x

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Microbiome in T2DM zebrafish. (A) Body weight gain after 4-weeks of feeding experiment. The T2DM (overfed) group had increased body weight compared to the control group. **p < 0.01, n = 10. (B) Fasting blood glucose (FBG) after the 4-week feeding experiment. The T2DM group exhibited higher FBG compared to the control group. **p < 0.01, n = 5. (C) α-diversity analysis. Whiskers in the boxplot represent minimum and maximum α-diversity values within each group. **p < 0.01, n = 4. (D,E) Median relative abundance of dominant bacteria at phylum level (D) and class level (E).