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. 2019 Jan 29;9:867. doi: 10.1038/s41598-018-37242-x

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Difference in bacterial compositions between T2DM zebrafish and control. (A) In the Proteobacteria phylum, Gamma-proteobacteria and Beta-proteobacteria were increased and decreased in T2DM zebrafish compared with the control group, respectively n = 4. (B) In the Gamma-proteobacteria class, Aeromonadales were increased in T2DM zebrafish compared to the control group n = 4. (C) In the Beta-proteobacteria class, Neisseriales and Burkholderiales were decreased in T2DM zebrafish compared to the control group n = 4. (D) The Bacteroidetes-to-Firmicutes (B/F) ratio in T2DM and control zebrafish. n = 4.