Table 3.
Estimated frequencies of inferred haplotypes.
| Haplotype frequency estimates** | ||||
|---|---|---|---|---|
| Reference | 2-SNP | 5-SNP | ||
| SIGMA | Mexican | 0.68 | 0.02 | 0.30 |
| HCHS/SOL | Mexican | 0.70 | 0.02 | 0.28 |
| Central American | 0.73 | 0.05 | 0.22 | |
| South American | 0.73 | 0.03 | 0.24 | |
| Cuban | 0.90 | 0.06 | 0.04 | |
| Dominican | 0.80 | 0.17 | 0.03 | |
| Puerto Rican | 0.82 | 0.11 | 0.07 | |
| 1000G phase 3 | AFR | 0.62 | 0.38 | 0.00 |
| AMR | 0.72 | 0.03 | 0.24 | |
| EAS | 0.90 | 0.00 | 0.10 | |
| EUR | 0.98 | 0.01 | 0.01 | |
| SAS | 0.99 | 0.00 | 0.00 | |
**Haplotype frequency estimates for HCHS/SOL were derived from unphased genotypes (as described in Methods); for 1000 G, they were calculated directly from phased genotypes. Listed in same order as haplotypes above.