Table 1.
Baseline features according to HFH status
| No HFH (n = 45) | HFH (n = 19) | P value | |
|---|---|---|---|
| Age (years) | 69 ± 1 | 71 ± 2 | 0.37 |
| Body mass index (kg/m2) | 32 ± 1 | 34 ± 2 | 0.27 |
| NT‐proBNP (pg/mL) | 332 (218–862) | 595 (222–1790) | 0.24 |
| Atrial fibrillation (%) | 36 | 37 | 0.92 |
| Hypertension (%) | 80 | 84 | 0.69 |
| IHD (%) | 31 | 32 | 0.97 |
| eGFR (mL/min/1.73 m2) | 65 ± 3 | 54 ± 4 | 0.08 |
| 6MWD (m) | 335 ± 16 | 316 ± 18 | 0.49 |
| Peak exercise workload (W) | 44 ± 3 | 40 ± 4 | 0.48 |
| Echocardiography | |||
| LVEF (%) | 47 ± 1 | 47 ± 1 | 0.66 |
| LAVI (mL/m2) | 34 ± 3 | 34 ± 3 | 0.88 |
| RAVI (mL/m2) | 35 ± 3 | 35 ± 3 | 0.95 |
| TAPSE (cm) | 2.0 ± 0.1 | 1.9 ± 0.1 | 0.52 |
| Resting haemodynamics | |||
| RA pressure (mmHg) | 9 ± 1 | 10 ± 1 | 0.15 |
| PAm pressure (mmHg) | 23 ± 1 | 25 ± 1 | 0.39 |
| PCWP (mmHg) | 17 ± 1 | 18 ± 1 | 0.40 |
| Cardiac index (L/min/m2) | 2.7 ± 0.1 | 2.7 ± 0.2 | 0.78 |
6MWD, 6 min walk distance; eGFR, estimated glomerular filtration rate; HFH, heart failure hospitalization; IHD, ischaemic heart disease; LAVI, left atrial volume index; LVEF, left ventricular ejection fraction; NT‐proBNP, N‐terminal pro‐brain natriuretic peptide; PAm, mean pulmonary artery; PCWP, pulmonary capillary wedge pressure; RA, right atrial; RAVI, right atrial volume index; TAPSE, tricuspid annular plane systolic excursion.
Values are mean ± SEM or median (25th–75th percentile interquartile range).