Table 1.
Baseline characteristics of adults patients who were admitted to ICU in 2012–2017.
| Variable | Total (21,236) | Mean | SD | |
|---|---|---|---|---|
| Sex: male | 12,434 (58.6%) | |||
| Age, year | 64.0 | 15.8 | ||
| Body mass index, kg m−2 | 23.7 | 3.9 | ||
| APACHE II | 20.0 | 10.0 | ||
| Comorbidities at ICU admission | ||||
| eGFR a ≥ 90 | 12,993 (61.2%) | |||
| 60 ≤ eGFR a < 90 | 4527 (21.3%) | |||
| 30 ≤ eGFR a < 60 | 2364 (11.1%) | |||
| eGFR a < 30 | 1352 (6.4%) | |||
| Hypertension | 9346 (44.0%) | |||
| Diabetes mellitus | 1969 (9.3%) | |||
| Ischemic heart disease | 538 (2.5%) | |||
| Cerebrovascular disease | 945 (4.4%) | |||
| Chronic obstructive lung disease | 921 (4.3%) | |||
| Liver disease (LC, hepatitis, fatty liver) | 683 (3.2%) | |||
| Anemia (Hb < 10 g dL−1) | 7569 (35.6%) | |||
| Cancer | 4308 (20.3%) | |||
| Characteristics of ICU admission | ||||
| Admission through emergency department | 12,042 (56.7%) | |||
| Admission department | ||||
| Internal medicine | 4671 (22.0%) | |||
| Neurologic center | 4975 (23.4%) | |||
| Cardiothoracic surgical department | 6875 (32.4%) | |||
| Other surgical department | 4715 (22.2%) | |||
| Length of ICU stay, day | 3.1 | 10.0 | ||
| Length of hospital stay, day | 12.9 | 20.1 | ||
| Preadmission statin use | 5756 (27.1%) | |||
| Total serum cholesterol at ICU adm, mg dL−1 | 138.2 | 47.9 | ||
| <160, mg dL−1 | 8584 (40.4%) | |||
| 160–200 mg dL−1 | 10,751 (50.6%) | |||
| >200 mg dL−1 | 1901 (9.0%) | |||
| Type of statin | ||||
| Atorvastatin | 3456 (16.3%) | |||
| Rosuvastatin | 1391 (6.6%) | |||
| Simvastatin | 396 (1.9%) | |||
| Pitavastatin | 346 (1.6%) | |||
| Other statin b | 167 (0.8%) | |||
| Total acute kidney injury | 5469 (25.8%) | |||
| Acute kidney injury stage ≥2 | 2216 (10.4%) | |||
| RRT after ICU adm within 72 h | 488 (2.3%) | |||
Presented as Number (percentage) or Mean value (standard deviation): a: eGFR (mL min −1 1.73 m−2): 186 × (Creatinine)−1.154 × (Age)−0.203 × (0.742 if female); b: Other statin: Pravastatin, Fluvastatin, and Lovastatin; ICU, intensive care unit; APACHE, acute physiology and chronic health evaluation; eGFR, estimated glomerular filtration rate; LC, liver cirrhosis; Hb, hemoglobin; RRT, renal replacement therapy.