Table 3.
Cox proportional regression analysis of one-year case fatality.
| HR | 95% CI | p Value | HR | 95% CI | p Value | |
|---|---|---|---|---|---|---|
| Univariate | ||||||
| Symptom-to-PCI time patient specific * | 1.014 | 1.007–1.022 | <0.001 | - | - | - |
| Symptom-to-PCI time annual † | 0.911 | 0.989–0.993 | <0.001 | - | - | - |
| Multivariable | ||||||
| Symptom-to-PCI time patient specific * | 1.024 | 1.015–1.034 | <0.001 | 1.024 | 1.015–1.034 | <0.001 |
| Symptom-to-PCI time annual † | 0.992 | 0.989–0.994 | <0.001 | 1.006 | 0.998–1.013 | 0.139 |
| Age >75 years | 3.30 | 3.10–3.52 | <0.001 | 3.30 | 3.10–3.52 | <0.001 |
| Male sex | 0.93 | 0.87–0.99 | 0.019 | 0.93 | 0.87–0.99 | 0.022 |
| Hypertension | 0.87 | 0.81–0.93 | <0.001 | 0.87 | 0.81–0.93 | <0.001 |
| Diabetes mellitus | 1.30 | 1.21–1.39 | <0.001 | 1.29 | 1.21–1.38 | <0.001 |
| Prior AMI | 1.06 | 0.96–1.17 | 0.28 | 1.06 | 0.96–1.18 | 0.23 |
| Prior PCI | 0.59 | 0.51–0.69 | <0.001 | 0.59 | 0.50–0.68 | <0.001 |
| Anterior STEMI | 1.15 | 1.08–1.22 | <0.001 | 1.15 | 1.08–1.22 | <0.001 |
| Pre-hospital cardiac arrest | 1.82 | 1.58–2.09 | 0.001 | 1.84 | 1.59–2.11 | <0.001 |
| Cardiogenic shock | 4.38 | 4.01–4.80 | <0.001 | 4.39 | 4.01–4.80 | <0.001 |
| Inter-hospital transfer | 1.11 | 1.04–1.18 | 0.001 | 1.12 | 1.05–1.19 | 0.001 |
| LVEF (per 10% more) | 0.62 | 0.60–0.63 | <0.001 | 0.62 | 0.60–0.63 | <0.001 |
| Year of admission † | - | - | - | 1.09 | 1.05–1.14 | <0.001 |
* per one hour more. † per one year change. HR—hazard ratio, CI—confidence interval, PCI—percutaneous coronary intervention, AMI—acute myocardial infarction, STEMI—ST-segment elevation myocardial infarction, LVEF—left ventricular ejection fraction.