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Agreement between phenotypic DST results and identified point mutations in the 23S rRNA gene at nucleotide positions, A2146 and A2147, conferring resistance to macrolides (N = 140).
| Phenotypic DST | |||
|---|---|---|---|
| Susceptible | Resistant | ||
| WGS | Susceptible a | 43 | 1 |
| Resistant b | 0 | 96 | |
a no mutation present at nucleotide positions, A2146 and A2147, in the 23S rRNA gene. b A mutation present at nucleotide positions, A2146 and A2147, in the 23S rRNA gene. DST: drug susceptibility testing.
