First Author (Year)	Finkelsztein EJ (2017) [26]
Title	Comparison of qSOFA and SIRS for predicting adverse outcomes of patients with suspicion of sepsis outside the intensive care unit
Journal	Critical Care
Reviewer	RL, KH, LL, MB, CG
Study sponsor	National Institutes of Health Grants
Study type	Prospectively Collected Data Retrospective Cohort (October 14—?)
Location	NY, USA
Participants Number Male/Female Median age (95% CI) Patient group	186 identified, 152 analyzed 31% male 64 (51–75) ED or ward to ICU, suspicion of infection
qSOFA criteria	Systolic blood pressure of ≤100 mmHg, respiratory rate of ≥22/minute, and altered mental status. The latter was not confined to a Glasgow Coma Scale score of <15, but it included any altered mentation, such as disorientation and somnolence
Primary outcome Other outcomes	All-cause in-hospital mortality ICU-free days from ICU admission to day 28, ventilator-free days from initiation of invasive mechanical ventilation to day 28, organ dysfunction-free days and renal dysfunction free days from ICU admission to day 14
Results	In-hospital AUC 0.74 (0.66–0.81), Sensitivity 90% (73–98), Specificity 42% (33–52)
Note