First Author (Year)	Guirgis (2017) [31]
Title	Development of a Simple Sequential Organ Failure Assessment Score for Risk Assessment of Emergency Department Patients with Sepsis
Journal	Journal of Intensive Care Medicine
Reviewer	RL, CG, KH
Study sponsor	National Institutes of General Medical Sciences and NIH Loan Repayment Program
Study type	Retrospective cohort (October 13–May 16)
Location	Jacksonville, FL, USA
Participants Number Male/Female Median age Patient group	3297 49% male 59 (48–70) Adult patients admitted through ED and discharge diagnosis of sepsis
qSOFA criteria	respiratory rate ≥22 breaths/ minute, altered mental status, or systolic blood pressure ≤100 mm Hg
Primary outcome Other outcomes	in-hospital mortality Sensitivities and specificities were calculated for patients with a discharge diagnosis of sepsis with a score of 2 or more for SOFA, qSOFA, or simple SOFA and were compared to patients with a score of <2
Results	In-hospital mortality AUC 0.68 for qSOFA sensitivity and specificity of qSOFA ≥2 were 38% and 86%, respectively
Note