First Author (Year)	Hwang SY (2018) [36]
Title	Low Accuracy of Positive qSOFA Criteria for Predicting 28-Day Mortality in Critically Ill Septic Patients During the Early Period After Emergency Department Presentation.
Journal	Annals of Emergency Medicine
Reviewer	RL, CG, KH
Study sponsor	Nil
Study type	Retrospective cohort study (August 08–September 14)
Location	Seoul, S Korea
Participants Number Male/Female Median age Patient group	1395 56% male 65 (55–73) Patients aged 18 years or older and who received a diagnosis of severe sepsis or septic shock (defined by SIRS) during their ED stay were included in analysis
qSOFA criteria	Systolic blood pressure of less than or equal to 100 mmHg, respiratory rate greater than or equal to 22 breaths/min, and altered mentation (GCS < 15 or <Alert on AVPU)
Primary outcome Other outcomes	28-day mortality In-hospital mortality, use of a vasopressor within 24 h after ED presentation, presence of cryptic shock, increase in a SOFA score of 2 points or more from the baseline, ICU admission, and mechanical ventilation
Results	28-day mortality AUC 0.58 (95% CI 0.55 to 0.62) on ED arrival for qSOFA ≥2
Note	Neutropenic patients included