First Author (Year)	Rannikko J (2017) [48]
Title	Sepsis-related mortality in 497 cases with blood culture-positive sepsis in an emergency department
Journal	International Journal of Infectious Diseases
Reviewer	RL, KH, LL,
Study sponsor	Competitive Research Financing of Tampere University Hospital
Study type	Retrospective cohort (March 12–February 14)
Location	Finland
Participants Number Male/Female Median Age (IQR) Patient group	800 identified, 497 analyzed 53% male 68 (58–78) ED patients with positive blood culture results
qSOFA criteria	Respiratory rate > 22/min, altered mentation (GCS < 15), and systolic blood pressure < 100 mmHg
Primary outcome Other outcomes	90-day mortality 28-day mortality
Results	Patients with missing data and under 18 years old are excluded, sample size 473. 28-day mortality AUC 0.71 (0.67–0.75), Sensitivity 0.65 (0.53–0.76), Specificity 0.77 (0.73–0.81), PPV 0.33 (0.28–0.39), NPV 0.93(0.9–0.95) +LR 2.9 (2.26–3.72), −LR 0.45 (0.32–0.62)
Note