First Author (Year)	Szakmany (2018) [54]
Title	Defining sepsis on the wards: Results of a multi-centre point-prevalence study comparing two sepsis definitions
Journal	Anaesthesia
Reviewer	RL, CG, MB
Study sponsor	Fiona Elizabeth Agnew Trust and the Welsh Intensive Care Society
Study type	Prospective observational study (19 October 2016)
Location	Wales
Participants Number Male/Female Median age Patient group	380 47% male 74 (61–83) Patients in the ED or in an acute in-patient ward setting with suspected or proven infection
qSOFA criteria	Systolic blood pressure ≤ 100 mmHg, respiratory rate ≥ 22 breaths/min, and altered mental status (defined as either a Glasgow Coma Scale score ≤ 13 or an Alert Voice Pain Unresponsive scale (AVPU) other than ‘Alert’)
Primary outcome Other outcomes	Mortality within 30 days Presence of organ dysfunction defined by SOFA score > 2 or the presence of ‘severe sepsis’
Results	AUC for 30-day mortality 0.57 (0.49–0.64) p = 0.07, Sen 0.22 (0.14–0.33), Spec 0.89 (0.85–0.92), PPV 0.34 (0.22–0.49), NPV 0.82 (0.77–0.85)
Note