Table 1.
Characteristics of the studies included in the systematic review of qSOFA for predicting prognosis.
| Study | Median Age (IQR) Mean Age ± SD |
Location | Male (%) | Sample Size | Study Type | Recruitment Period |
|---|---|---|---|---|---|---|
| Amland et al. [15] | 65 (51–76) | US | 48 | 5992 | Retrospective | January 2016–March 2016 |
| April et al. [16] | 72 (60–79) | Texas, US | 58.9 | 214 | Retrospective | August 2012–February 2015 |
| Askim et al. [17] | 62 (41–78) | Norway | 53 | 1535 | PCDRC | January 2012–December 2012 |
| Boulos et al. [18] | 68.5 ± 17.4 | Monash, Australia | 52 | 646 | Retrospective | January 2015–December 2015 |
| Brabrand et al. [19] | 65 (50–77) | Denmark | 49.2 | 4931 | Retrospective | October 2008–May 2010 |
| Burnham et al. [20] | 61.1 (51.6–69.8) | Missouri, USA | 52 | 510 | Retrospective | June 2009–December 2013 |
| Chen et al. [21] | 73 (62–79) | Beijing, China | 59 | 1641 | PCDRC | January 2012–May 2014 |
| Churpek et al. [22] | 58 ± 18 | Chicago, US | 47 | 30,677 | Retrospective | November 2008–January 2016 |
| de Groot et al. [23] | 61.1 ± 17 | Holland | 57.7 | 2280 | PCDRC | April 2011–February 2016 |
| Donnelly et al. [24] | 68 (61–75) | USA | 47.8 | 2593 | Retrospective | January 2003–October 2007 |
| Du et al. [25] | 56.4 ± 18.1 | Sichuan, China | 65.7 | 565 | Retrospective | August 2015–July 2016 |
| Finkelsztein et al. [26] | 64 (51–75) | New York, USA | 31 | 152 | PCDRC | October 2014–July 2016 |
| Forward et al. [27] | 70 ± ? | Sydney, Australia | 55 | 161 | Prospective | May 2015–August 2015 |
| Freund et al. [28] | 67 (48–81) | Europe | 53 | 879 | Prospective | May 2016–June 2016 |
| Giamarellos-Bourboulis et al. [29] | 76 (IQR: 22) | Greece | ? | 3436 | Retrospective | May 2006–December 2015 |
| Gonzalez del Castillo et al. [30] | 83.6 ± 5.6 | Spain | 50.8 | 1071 | Prospective | October 2015–April 2016 |
| Guirgis et al. [31] | 59 (48–70) | Florida, USA | 49 | 3297 | Retrospective | October 2013–May 2016 |
| Haydar et al. [32] | 71 (range 18–102) | Portland, USA | 55 | 199 | Retrospective | September 2014–September 2015 |
| Henning et al. [33] | 58.4 ± 20.1 | USA | 52.2 | 7754 | PCDRC | December 2003–September 2006 |
| Ho et al. [34] | 57.1 (41–70) | Perth, Australia | 61 | 2322 | PCDRC | January 2008–December 2013 |
| Hu et al. [35] | ? | Zhejiang, China | 62.6 | 329 | Retrospective | January 2015–June 2015 |
| Hwang et al. [36] | 65 (55–73) | Seoul, South Korea | 56 | 1395 | Retrospective | August 2008–September 2014 |
| Innocenti et al. [37] | 75 ± 14 | Florence, Italy | 53 | 742 | Retrospective | June 2008–April 2016 |
| Khwannimit et al. [38] | 62 (45–75) | Songkhla, Thailand | 56.1 | 2350 | Retrospective | January 2007–December 2016 |
| Kim et al. [39] | 72 (59.5–80) | Seoul, South Korea | 62.4 | 125 | Retrospective | January 2014–December 2014 |
| Kolditz et al. [40] | 63 (?) | Germany | 56 | 9327 | Retrospective | October 2002–June 2015 |
| LeGuen et al. [41] | 72 (57–82) | Victoria, Australia | 48 | 258 | Prospective | 6 June 2016, 10 July 2016 |
| Moskowitz et al. [42] | 63.8 ± 18.1 | USA | 50.9 | 24,164 | Retrospective | January 2010–December 2014 |
| Muller et al. [43] | 66 (50–76) | Switzerland | 64.5 | 527 | Retrospective | June 2011–May 2013 |
| Park et al. [44] | 67.4 ± 17.6 | Seoul, South Korea | 45 | 1009 | Retrospective | March 2007–February 2016 |
| Peake et al. [45] | 62.9 ± 16.5 | Australasia | 59.7 | 1591 | PCDRC | October 2008–April 2014 |
| Quinten et al. [46] | 60 (48–71) | Netherlands | 56 | 193 | PCDRC | August 2012–April 2014 |
| Raith et al. [47] | 62.9 ± 17.4 | Australasia | 55.4 | 184,875 | Retrospective | January 2000–December 2015 |
| Rannikko et al. [48] | 68 (58–78) | Finland | 53 | 467 | Retrospective | March 2012–February 2014 |
| Ranzani et al. [49] | 66.1 ± 19 | Barcelona + Valencia, Spain | 62.2 | 6874 | PCDRC | January 1996–December 2015 |
| Seymour et al. [50] | 61 ± 19 | US and Germany | 43 | 74,453 | Retrospective | January 2010–December 2012 |
| Siddiqui et al. [51] | 64.4 ± 12.9 | Singapore | 60 | 58 | Retrospective | January 2015–December 2015 |
| Singer et al. [52] | 54 ± 21 | New York, USA | 47 | 200 | Retrospective | January 2014–March 2015 |
| Sterling et al. [53] | 60 ± 16.7 | USA | ? | 22,530 | PCDRC | August 2004–January 2009 |
| Szakmany et al. [54] | 74 (61–83) | Wales, UK | 47 | 380 | Prospective | 19 October 2016 |
| Tusgul et al. [55] | 80 (69–87) | Switzerland | 52.1 | 886 | Retrospective | January 2012–December 2012 |
| Umemura et al. [56] | ? | Japan | 59.7 | 387 | PCDRC | June 2010–May 2011 |
| Wang J et al. [57] | 73 (60–79) | Beijing, China | 61.8 | 477 | PCDRC | July 2015–December 2015 |
| Wang S et al. [58] | 63 ± 17.3 | Chenzhou, China | 69.5 | 311 | Retrospective | July 2012–June 2016 |
| Williams et al. [59] | 49 (30–69) | Brisbane, Australia | 51.3 | 8871 | PCDRC | October 2007–May 2011 |
qSOFA, quick Sepsis-related Organ Failure Assessment; IQR, Interquartile Range; PCDRC, Prospectively Collected Data Retrospective Cohort; ?, Information not available.