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. 2019 Jan 16;10:2041731418824797. doi: 10.1177/2041731418824797

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© The Author(s) 2019

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — Chondrogenic differentiation in engineered cartilage in vitro. (a) Changes in mRNA expression levels and (b) GAG amount normalized to DNA amount, and the production of (c) aggrecan and (d) type-2 collagen in the hASCs injected with alginate hydrogel or cartilage-derived hydrogel (n = 4 per experimental group for real-time qPCR; n = 3 per experimental group for biochemical assay; ***p < 0.001; ****p < 0.0001; scale bar = 200 μm).