Table 3.
Association between FVC and HRQOL scores in Dongfeng-Tongji cohort participants.
| Estimated Changes (95% CI) by Continuous FVC | Estimated Changes (95% CI) by Tertile of FVC | ||||||
|---|---|---|---|---|---|---|---|
| β | p Value | T1 (<2.12 L) | T2 (2.12–2.69 L) | T3 (≥2.69 L) | p Trend | ||
| N | 2767 | 2807 | 2824 | ||||
| Median (L) | 1.78 | 2.39 | 3.08 | ||||
| Total score | Univariate model | 1.36 (1.04,1.69) | <0.0001 * | 0 (reference) | 1.43 (0.88,1.98) * | 2.12 (1.57,2.67) * | <0.0001 * |
| Model 1 † | 0.83 (0.46,1.20) | <0.0001 * | 0 (reference) | 0.73 (0.17,1.30) * | 1.18 (0.56,1.80) * | 0.0002 * | |
| Model 2 ‡ | 0.84 (0.47,1.21) | <0.0001 * | 0 (reference) | 0.75 (0.19,1.32) * | 1.20 (0.58,1.82) * | 0.0002 * | |
| Model 3 § | 0.63 (0.26,1.00) | 0.0010 * | 0 (reference) | 0.61 (0.04,1.17) * | 0.89 (0.27,1.51) * | 0.0056 * | |
| Physical health domain score | Univariate model | 2.90 (2.38,3.42) | <0.0001 * | 0 (reference) | 2.33 (1.44,3.22) * | 4.27 (3.38,5.16) * | <0.0001 * |
| Model 1 † | 1.85 (1.25,2.45) | <0.0001 * | 0 (reference) | 0.98 (0.07,1.89) * | 2.36 (1.36,3.36) * | <0.0001 * | |
| Model 2 ‡ | 1.88 (1.29,2.48) | <0.0001 * | 0 (reference) | 1.03 (0.11,1.94) * | 2.41 (1.41,3.41) * | <0.0001 * | |
| Model 3 § | 1.67 (1.07,2.28) | <0.0001 * | 0 (reference) | 0.89 (−0.02,1.80) | 2.08 (1.07,3.08) * | <0.0001 * | |
| Psychological state domain score | Univariate model | 1.27 (0.87,1.67) | <0.0001 * | 0 (reference) | 1.58 (0.90,2.27) * | 2.12 (1.44,2.81) * | <0.0001 * |
| Model 1 † | 0.50 (0.04,0.96) | 0.0343 * | 0 (reference) | 0.82 (0.11,1.52) * | 0.88 (0.10,1.65) * | 0.0294 * | |
| Model 2 ‡ | 0.51 (0.05,0.97) | 0.0309 * | 0 (reference) | 0.83 (0.13,1.54) * | 0.89 (0.12,1.67) * | 0.0266 * | |
| Model 3 § | 0.25 (−0.21,0.72) | 0.2850 | 0 (reference) | 0.64 (−0.06,1.35) | 0.54 (−0.24,1.32) | 0.1864 | |
| Social relationships domain score | Univariate model | 0.80 (0.41,1.19) | <0.0001 * | 0 (reference) | 1.09 (0.42,1.76) * | 1.24 (0.58,1.91) * | 0.0003 * |
| Model 1 † | 0.71 (0.26,1.16) | 0.0021 * | 0 (reference) | 0.77 (0.08,1.46) * | 1.05 (0.29,1.80) * | 0.0074 * | |
| Model 2 ‡ | 0.72 (0.27,1.17) | 0.0018 * | 0 (reference) | 0.78 (0.09,1.47) * | 1.06 (0.30,1.82) * | 0.0066 * | |
| Model 3 § | 0.49 (0.03,0.95) | 0.0356 * | 0 (reference) | 0.62 (−0.08,1.31) | 0.72 (−0.04,1.49) | 0.0670 | |
| Environment domain score | Univariate model | 0.49 (0.12,0.87) | 0.0103 * | 0 (reference) | 0.73 (0.08,1.37) * | 0.84 (0.19,1.48) * | 0.0214 * |
| Model 1 † | 0.25 (−0.19,0.69) | 0.2601 | 0 (reference) | 0.37 (−0.29,1.04) | 0.44 (−0.29,1.17) | 0.2444 | |
| Model 2 ‡ | 0.26 (−0.18,0.69) | 0.2469 | 0 (reference) | 0.38 (−0.28,1.05) | 0.45 (−0.28,1.18) | 0.2324 | |
| Model 3 § | 0.09 (−0.35,0.54) | 0.6739 | 0 (reference) | 0.27 (−0.40,0.94) | 0.22 (−0.52,0.95) | 0.5796 | |
* p < 0.05 is considered statistically significant. † Model 1: adjusted for age and gender. ‡ Model 2: adjusted for variables in model 1 plus BMI. § Model 3: adjusted for variables in model 2 plus marriage status, educational level, smoking status, passive smoking, alcohol consumption and physical activity.