Table 4.
Association between FEV1 and HRQOL scores in Dongfeng-Tongji cohort participants.
| Estimated Changes (95% CI) by Continuous FEV1 | Estimated Changes (95% CI) by Tertile of FEV1 | p Trend | |||||
|---|---|---|---|---|---|---|---|
| β | p Value | T1 (<1.86 L) | T2 (1.86–2.33 L) | T3 (≥2.33 L) | |||
| N | 2797 | 2769 | 2832 | ||||
| Median (L) | 1.55 | 2.09 | 2.64 | ||||
| Total score | Univariate model | 1.54 (1.17,1.92) | <0.0001 * | 0 (reference) | 1.53 (0.98,2.08) * | 2.09 (1.54,2.64) * | <0.0001 * |
| Model 1 † | 0.73 (0.29,1.16) | 0.0011 * | 0 (reference) | 0.76 (0.19,1.33) * | 0.93 (0.31,1.56) * | 0.0031 * | |
| Model 2 ‡ | 0.76 (0.33,1.20) | 0.0006 * | 0 (reference) | 0.78 (0.22,1.35) * | 0.97 (0.35,1.60) * | 0.0021 * | |
| Model 3 § | 0.53 (0.09,0.97) | 0.0175 * | 0 (reference) | 0.61 (0.04,1.17) * | 0.69 (0.07,1.32) * | 0.0287 * | |
| Physical health domain score | Univariate model | 3.21 (2.60,3.82) | <0.0001 * | 0 (reference) | 3.01 (2.12,3.90) * | 3.88 (2.99,4.77) * | <0.0001 * |
| Model 1 † | 1.62 (0.92,2.33) | <0.0001 * | 0 (reference) | 1.51 (0.59,2.42) * | 1.47 (0.46,2.47) * | 0.0040 * | |
| Model 2 ‡ | 1.71 (1.00,2.41) | <0.0001 * | 0 (reference) | 1.56 (0.65,2.47) * | 1.55 (0.55,2.56) * | 0.0022 * | |
| Model 3 § | 1.46 (0.75,2.17) | <0.0001 * | 0 (reference) | 1.38 (0.47,2.30) * | 1.25 (0.24,2.27) * | 0.0142 * | |
| Psychological state domain score | Univariate model | 1.50 (1.03,1.97) | <0.0001 * | 0 (reference) | 1.43 (0.74,2.11) * | 2.19 (1.51,2.87) * | <0.0001 * |
| Model 1 † | 0.47 (−0.07,1.02) | 0.0890 | 0 (reference) | 0.64 (−0.06,1.35) | 0.80 (0.02,1.58) * | 0.0421 * | |
| Model 2 ‡ | 0.50 (−0.05,1.04) | 0.0732 | 0 (reference) | 0.66 (−0.05,1.37) | 0.83 (0.05,1.61) * | 0.0357 * | |
| Model 3 § | 0.22 (−0.33,0.77) | 0.4258 | 0 (reference) | 0.45 (−0.25,1.16) | 0.51 (−0.27,1.16) | 0.1979 | |
| Social relationships domain score | Univariate model | 0.92 (0.46,1.38) | <0.0001 * | 0 (reference) | 1.03 (0.36,1.69) * | 1.31 (0.65,1.98) * | 0.0001 * |
| Model 1 † | 0.68 (0.14,1.21) | 0.0130 * | 0 (reference) | 0.62 (−0.07,1.31) | 0.98 (0.22,1.74) * | 0.0116 * | |
| Model 2 ‡ | 0.70 (0.17,1.23) | 0.0100 * | 0 (reference) | 0.64 (−0.06,1.33) | 1.00 (0.24,1.76) * | 0.0096 ** | |
| Model 3 § | 0.46 (−0.07,1.00) | 0.0914 | 0 (reference) | 0.45 (−0.25,1.14) | 0.71 (−0.06,1.47) | 0.0692 | |
| Environment domain score | Univariate model | 0.54 (0.10,0.98) | 0.0169 * | 0 (reference) | 0.66 (0.02,1.31) * | 0.97 (0.33,1.61) * | 0.0031 * |
| Model 1 † | 0.13 (−0.38,0.64) | 0.6221 | 0 (reference) | 0.27 (−0.40,0.93) | 0.49 (−0.25,1.22) | 0.1925 | |
| Model 2 ‡ | 0.15 (−0.37,0.66) | 0.5742 | 0 (reference) | 0.28 (−0.39,0.94) | 0.51 (−0.23,1.24) | 0.1755 | |
| Model 3 § | −0.02 (−0.54,0.50) | 0.9439 | 0 (reference) | 0.15 (−0.52,0.82) | 0.30 (−0.44,1.04) | 0.4218 | |
* p < 0.05 is considered statistically significant. † Model 1: adjusted for age and gender. ‡ Model 2: adjusted for variables in model 1 plus BMI. § Model 3: adjusted for variables in model 2 plus marriage status, educational level, smoking status, passive smoking, alcohol consumption and physical activity.