Table 5.
Association between lung function (FVC and FEV1) and HRQOL scores, stratified by comorbidities and no-comorbidities.
| Estimated Changes (95% CI) by Continuous FVC ‡ | Estimated Changes (95% CI) by Continuous FEV1 ‡ | ||||
|---|---|---|---|---|---|
| β | p Value | β | p Value | ||
| No comorbidities † (n = 3871) | Total score | 1.31 (0.76,1.85) | <0.0001 * | 1.06 (0.42,1.69) | 0.0011 * |
| Physical health domain score | 1.76 (0.94,2.59) | <0.0001 * | 1.64 (0.67,2.60) | 0.0009 * | |
| Psychological state domain score | 1.10 (0.42,1.78) | 0.0015 * | 0.76 (−0.04,1.56) | 0.0626 | |
| Social relationships domain score | 1.40 (0.73,2.06) | <0.0001 * | 1.21 (0.43,2.00) | 0.0024 * | |
| Environment domain score | 0.96 (0.32,1.60) | 0.0031 * | 0.61 (−0.13,1.36) | 0.1077 | |
| Comorbidities † (n = 4527) | Total score | −0.04 (−0.55,0.47) | 0.8781 | −0.04 (−0.64,0.57) | 0.9055 |
| Physical health domain score | 1.32 (0.48,2.16) | 0.0022 * | 0.97 (−0.02,1.97) | 0.0557 | |
| Psychological state domain score | −0.49 (−1.14,0.15) | 0.1303 | −0.27 (−1.03,0.49) | 0.4821 | |
| Social relationships domain score | −0.31 (−0.94,0.32) | 0.3346 | −0.22 (−0.97,0.52) | 0.5579 | |
| Environment domain score | −0.68 (−1.29,−0.06) | 0.0302 * | −0.63 (−1.35,0.10) | 0.0889 | |
* p < 0.05 is considered statistically significant. † Comorbidities: including gallstone, rhinitis, hypertension, hyperlipemia and diabetes. ‡ Adjusted for age, gender, BMI, marriage status, educational level, smoking status, passive smoking, alcohol consumption and physical activity.