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The role of exosomes in Epithelial-to-Mesenchymal Transition (EMT) and tumor progression is depicted. (A) Exosomes originate from the multivesicular bodies that release them by fusing with the cellular membrane. (B) Exosome cargo content of DNA, RNA (including ncRNA) and proteins specifically mediates cell–cell communication in EMT and in the associated tumor progression to promote different outcomes.
